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Cat#：211P29
序列（三字母）：H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH? (Disulfide bonds between Cys3 and Cys1?/Cys? and Cys1?)
序列（單字母）：ALCNCNRIIIPHMCWKKCGKK-NH?
分子式：C???H???N??O??S?
分子量：2455.11
CAS#：58694-52-3
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
應(yīng)用：Ion Channel Modulating Agents
描述：Tertiapin (TPN), a potent inhibitor of the inward-rectifier K? channels, blocked a G-protein-gated channel (GIRK1/4) and the ROMK1 channel with nanomolar affinities, however a closely related channel, IRK1, was insensitive to tertiapin. Thus, tertiapin will be a powerful ligand for purifying functional channels as well as for screening pharmaceutical agents against these channels.